Cialis is the brand name for the drug Tadalafil, used primarily for the treatment of erectile dysfunction in men. It works in a slightly different way from the famous ED treatment Viagra, though it produces the same result: improved ability to gain and sustain an erection. Cialis in comparison lasts longer than Sildenafil, the active ingredient in Viagra. In this guide we’ll explain what Cialis does, who might need it, and what to do if you’d like to try it.

Cialis Treatment

Cialis is prescribed to ED patients for myriad reasons: they may experience impotency problems due to age, illness, other medication, stress, or various other issues. It comes in doses ranging from 2.5mg to 20mg. Cialis is a film-coated, almond-shaped yellow tablet. The tablets become a brighter shade of yellow as dosage increases. Cialis is swallowed whole with a full glass of water, and taking with or without food is down to preference. Generic Tadalafil, that works in the same way as Cialis, can generally be obtained for a cheaper price. A doctor can advise which solution is best for individuals.

A main difference between Cialis and Viagra is that Cialis is designed to be taken every day, ideally at the same time, whereas Viagra is to be used on an as-and-when basis, an hour before sexual intercourse. Cialis is a great alternative for those who find having to take a pill precisely an hour before sex understandably inconvenient. Its effects stay in the bloodstream so that the patient is ‘ready to go’ whenever they like. However, patients should allow up to an hour for the drug’s effect to take hold. Sexual stimulation is required for users to achieve an erection: they don’t just happen unprovoked.


How Does Tadalafil Work?

Tadalafil is an inhibitor of the PDE5 (phosphodiesterase-type-5) enzyme. This enzyme breaks down a substance called Cyclic GMP. C-GMP’s main action is to relax or widen arteries and blood vessels. When it is broken down, blood vessels are constricted and allow less blood to flow. This can contribute to a man’s inability to sustain an erection long enough to complete sexual intercourse.

PDE5 inhibitors prevent the breakdown of C-GMP, therefore meaning that blood vessels are no longer constricted. This increases blood flow to the penis, allowing for better, longer-lasting erections. For this reason, Cialis is a popular ED medication.

C-GMP was also found to be produced in the lungs, and so PDE5 inhibitors like Tadalafil were explored as a possible treatment for pulmonary arterial hypotension (PAH), a condition causing pain due to high blood pressure in the lungs and heart. The treatment was a success, and therefore Tadalafil under the brand name of Adcirca can be prescribed to PAH patients to reduce discomfort and increase their ability to exercise and go about daily life.

Side Effects


  • Common side effects identified during the drug’s clinical trials on 15,000 people included: headaches, upset stomach, acid reflux, indigestion, flushing, muscle aches, back pain, and a congested nose.
  • Patients taking nitrate medication, usually for heart conditions, should not take generic Tadalafil or Cialis. Taking both medications in conjunction could cause blood pressure to rapidly drop to dangerously low levels, known as hypotension.
  • Similarly, recreational sex drugs ‘poppers’ (alkyl nitrites and amyl nitrites) should not be used within 48 hours after taking Cialis as this can also induce serious hypotension.
  • Cialis’s manufacturers Lilly ICOS state that if a man experiences any of the following during sexual intercourse after taking the drug, he should seek immediate medical help: pain, numbness or a tingling sensation in the jaw, chest, neck or arms; nausea; or dizziness.
  • Grapefruit or its juice should not be consumed while taking Tadalafil: the fruit can increase the amount of Tadalafil in the blood.
  • If a man sustains an erection for more than 4 hours (a condition known as priapism) after taking Cialis, he should seek medical help. An erection lasting this long could cause permanent damage to the penis.
  • In rare cases after taking Cialis, the blood flow to the eye can be compromised, causing loss of vision. Patients with pre-existing diabetes, high cholesterol, heart disease or hypertension should be especially vigilant of this effect.
  • Cialis is not advised to be taken for those who have: heart disease, angina, hypertension, hypotension, sickle cell anaemia, leukaemia, haemophilia, kidney or liver disease, or have suffered a stroke within the last 6 months.

This is not a complete list. Follow the advice of a doctor before taking Cialis.

I’d Like to Try Cialis – What Do I Do?

It’s not always easy to talk about impotency with a doctor – but if ED is seriously affecting a person’s relationship and sex life, it should be considered. Doctors treat this issue all the time, and it’s nothing to be ashamed of. There are several simple treatment options available, including Cialis.

As previously explained, Cialis is taken daily at a dose suitable for each individual depending on their tolerance and needs. Only a qualified doctor can recommend this dose. It is essential that a patient explains their medical history and specific current condition to a doctor to find out which treatment type and dose will work for them. It’s also vital so that any conflicts of medication or pre-existing conditions can be identified.

Cialis can be obtained by visiting a doctor’s surgery or from a licensed online pharmacy such as UK Meds. This type of pharmacy is growing in popularity due to convenience and often because they offer discounted medications than buying from a physical pharmacy.

Licenced e-pharmacies are perfectly legal and safe; however, consumers should be hyper-aware of bogus e-pharmacies selling fake drugs when buying online. Always look for government registration on such websites. Legal e-pharmacies still require a prescription to be made via an online consultation with a real accredited pharmacist or doctor. If the website you’re looking at doesn’t require patients to undergo a consultation, do not purchase from it.

Online consultations require prospective patients to fill out a form and wait for a doctor to give the go-ahead for medication to be sent out. If the patient is considered a good candidate for the medication by a doctor, they can fill out their prescriptions from that e-pharmacy from then on. This provides greater convenience for patients who dislike in-person doctor’s appointments, have limited mobility, or want to take advantage of cheaper online drug prices.

About Michael DouekMichael Douek is Professor of Surgical Oncology and Breast Surgeon at King's College London and Honorary Consultant Surgeon at Guy's and St Thomas' Hospital. He has a research interest in developing and evaluating novel techniques for cancer surgery. Besides developing a novel magnetic technique for sentinel node biopsy and lesion localization, he is one of the pioneers of intra-operative radiotherapy for breast cancer and set up the first prospective trial of a biological device for breast implant reconstuction (POBRAD Trial of Acellular Dermal Matrix). He is currently Chief Investigator of a number of internationl clinical trials. In 2015, he was awarded a prestigious Hunterian Professorship by the Royal College of Surgeons of England.Michael Douek Facebook Michael Douek Google Plus Michael Douek Twitter Michael Douek Medium Michael Douek Wordpress Michael Douek Blogger