Cialis is most often used for the treatment of erectile dysfunction (ED) in men, for its effects on allowing improved blood flow to the penis and helping patients to gain an erection as a result. Cialis is included in a group of drugs known as PDE5 inhibitors, which also includes Sildenafil or Viagra.

Cialis, or its generic drug counterpart Tadalafil, can also be used in the treatment of two other conditions: pulmonary arterial hypertension (PAH) and benign prostatic hyperplasia.

Erectile Dysfunction

PDE5 inhibitors prevent the constriction of blood vessels in the penis, allowing more blood to enter the corpus cavernosum – the erectile tissue which fills with blood during sexual stimulation to result in an erection. Patients with ED take Cialis or other PDE5 inhibitors to prevent bodily chemical reactions that cause blood vessel restrictions. The drugs enable the penile blood vessels to relax, allowing adequate blood flow to the corpus cavernosum to achieve and maintain an erection long enough to complete sexual intercourse.

Cialis for ED is usually prescribed as a daily medication but can also be prescribed as a ‘use when needed’ drug. The dosages vary markedly between these two variants, so it’s incredibly important to be aware of these to avoid overdose, especially if a patient chooses to buy online.

Guidelines for daily versus as-needed dosages are:

  • Once-per-day dose is usually 2.5mg-5mg.
  • As-needed dose is 10mg-20mg.

All dosages should be prescribed by a doctor, dependent on an individual’s unique circumstances, condition and medical history. A patient should not guess his own dose: overdose on Cialis can cause a host of dangerous side effects, including life-threateningly high blood pressure. Always seek the advice of a medical professional before taking a new drug.

Pulmonary Arterial Hypertension

PDE5 also causes restriction of blood vessels in the lungs. This can result in high blood pressure surrounding the heart and lungs, causing pain and difficulty exercising and moving. These are symptoms associated with pulmonary arterial hypertension (PAH).

Inhibiting PDE5 from acting on the blood vessels allows them to relax and become wider, so that greater amounts of blood can flow faster between the heart and lungs. This helps to reduce blood pressure in the area and improves oxygen transportation throughout the whole body, helping PAH patients to feel more energised and become more mobile.

An average dose of Tadalafil (under the brand name Adcirca) for PAH is 40mg, taken as two 20mg tablets at the same time, once per day.

Benign Prostatic Hyperplasia

Tadalafil, the active ingredient in Cialis, can also be used to relieve the symptoms of BPH – a swollen or enlarged prostate. This condition is thought to occur naturally, mostly in older men, as the prostate grows with age. An enlarged prostate can increase the need to urinate, cause difficulty urinating, or can even prevent urination from happening, causing pain and strain in the bladder.

Tadalafil (as Cialis or its generic drug form) is prescribed to BPH patients as it helps to treat these symptoms, and it is thought to work by relaxing the muscles in the bladder and prostate. It is often used in conjunction with Finasteride, a drug that works to shrink the prostate to a smaller size and prevent these symptoms from occurring.

For BPH patients, a Tadalafil dose of 5mg per day, taken at the same time each day with or without food, is the general starter dose. Doctors can decide to increase or decrease a patient’s dose after supervision of their condition.